Publication2023
Pol32, an accessory subunit of DNA polymerase delta, plays an essential role in genome stability and pathogenesis of Candida albicans
The record
- Type
- Publication
- Date
- 1 January 2023
- Level
- National
- Journal
- Gut Microbes
- Volume
- 15
- Issue
- 1
- Published
- 1 January 2023
- DOI
- 10.1080/19490976.2022.2163840
- Scopus ID
- 85145539920
- ISSN
- 19490976
- Authors
- 5
- Open access
- Yes
- Citations
- 13
- International co-authorship
- No
- Co-author countries
- IN
Classification
Every label below carries the reasoning it was assigned on, the confidence band it was assigned in, and what produced it. The rubric is published.
UN Sustainable Development Goals
3.3 End the epidemics of AIDS, tuberculosis, malaria, neglected tropical diseases, hepatitis and water-borne diseases
Genetic analysis demonstrates Pol32 DNA polymerase subunit is essential for Candida albicans genome stability and virulence; loss of pol32 confers azole resistance but attenuates pathogenesis and bloodstream infection.
- High confidence
- The subject matter is a strong and direct inference from the record type, the funding or organising body, or the programme context, even where the title alone is thin. Example: an ICMR-funded project against SDG 3, on the strength of the agency.
- Judged
- Judged against the published classification rubric, under the rubric and prompt versions recorded with the run that produced it.
- Produced by
- claude-haiku-4-5-20251001, under kortex-publication-v1
9.5 Enhance scientific research, upgrade technological capabilities, and increase researchers and R&D spending
Genomic research advances understanding of fungal pathogenesis mechanisms relevant to antifungal drug and vaccine development.
- Moderate confidence
- The alignment is plausible and defensible but rests on an assumption a reasonable reviewer could decline. Published, and surfaced in the review queue for a human to confirm or override.
- Produced by
- claude-haiku-4-5-20251001, under kortex-publication-v1
Viksit Bharat @2047
vb-1.2 Health and well-being
Candida pathogenesis research identifies therapeutic targets for improving treatment of invasive fungal infections in immunocompromised patients.
- Produced by
- claude-haiku-4-5-20251001, under kortex-publication-v1
Each label above carries the instrument and the version that produced it. How each classification is reached.
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- Source rows resolved into this record
- 1
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Citing this record
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KIIT Deemed to be University. “Pol32, an accessory subunit of DNA polymerase delta, plays an essential role in genome stability and pathogenesis of Candida albicans”. Kortex.