Publication2022
CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis
The record
- Type
- Publication
- Date
- 3 November 2022
- Level
- National
- Journal
- Oncogene
- Volume
- 41
- Issue
- 45
- Pages
- 4929-4940
- Published
- 3 November 2022
- DOI
- 10.1038/s41388-022-02475-8
- Scopus ID
- 85139194117
- ISSN
- 09509232
- Authors
- 11
- Open access
- Yes
- Citations
- 19
- International co-authorship
- No
- Co-author countries
- IN
Classification
Every label below carries the reasoning it was assigned on, the confidence band it was assigned in, and what produced it. The rubric is published.
UN Sustainable Development Goals
3 Ensure healthy lives and promote well-being for all at all ages
CRISPR kinome screening identified MINK1 as druggable target overcoming 5FU chemotherapy resistance in oral squamous cell carcinoma.
- Certain confidence
- The record states the subject matter explicitly. A reader shown only the title and this goal would agree without hesitation. Example: a workshop titled "Renewable Energy and Smart Grid" against SDG 7.
- Judged
- Judged against the published classification rubric, under the rubric and prompt versions recorded with the run that produced it.
- Produced by
- claude-haiku-4-5-20251001, under kortex-publication-v1
Viksit Bharat @2047
vb-1.2 Health and well-being
Cancer therapy research enabling treatment of drug-resistant oral cancer.
- High confidence
- The subject matter is a strong and direct inference from the record type, the funding or organising body, or the programme context, even where the title alone is thin. Example: an ICMR-funded project against SDG 3, on the strength of the agency.
- Produced by
- claude-haiku-4-5-20251001, under kortex-publication-v1
Each label above carries the instrument and the version that produced it. How each classification is reached.
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Provenance
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- Source rows resolved into this record
- 1
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Citing this record
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KIIT Deemed to be University. “CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis”. Kortex.