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by IQAC KIITKIIT Deemed to be University — Internal Quality Assurance Cell

Publication2024

CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness

The record

Type
Publication
Date
15 March 2024
Level
International — held abroad
Journal
Science Advances
Volume
10
Issue
11
Published
15 March 2024
DOI
10.1126/sciadv.adh9547
Scopus ID
85188201178
ISSN
23752548
Authors
28
Open access
Yes
Citations
11
International co-authorship
Yes
Co-author countries
CN, DK, GB, IN, US

Classification

Every label below carries the reasoning it was assigned on, the confidence band it was assigned in, and what produced it. The rubric is published.

UN Sustainable Development Goals

  1. 3 Ensure healthy lives and promote well-being for all at all ages

    GoalPrimaryHigh confidenceJudged

    Discovery that CKLF chemokine-induced CD4+ cell recruitment creates immunosuppressive tumor microenvironment reveals therapeutic target for MYCN-driven neuroblastoma immunotherapy.

    High confidence
    The subject matter is a strong and direct inference from the record type, the funding or organising body, or the programme context, even where the title alone is thin. Example: an ICMR-funded project against SDG 3, on the strength of the agency.
    Judged
    Judged against the published classification rubric, under the rubric and prompt versions recorded with the run that produced it.
    Produced by
    claude-haiku-4-5-20251001, under kortex-publication-v1
  2. 17.6 Enhance North-South, South-South and triangular cooperation on science, technology and innovation, and knowledge sharing

    TargetSecondaryHigh confidenceRule-derivedrule sdg17-structural-v1

    Structural signal: co-authorship outside India.

    Rule-derived
    Emitted by a deterministic rule from structural signals rather than judged from the record’s text. The rule carries a version, so rule-derived and judged labels stay separable.
    Produced by
    sdg17-structural-v1, under kortex-publication-v1

Viksit Bharat @2047

  1. vb-1.2 Health and well-being

    Sub-themePrimaryHigh confidenceJudged

    Cancer immunotherapy research through tumor microenvironment modulation addresses high-risk childhood cancer treatment and survival outcomes.

    Produced by
    claude-haiku-4-5-20251001, under kortex-publication-v1

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KIIT Deemed to be University. “CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness”. Kortex.

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